Only chemotherapeutic combination medicines were available as combination treatments for the treatment of CLL. Combinations that have previously been allowed were few. Nonetheless, strict regulatory requirements are predicted to impede market.
A blood and bone marrow condition known as Chronic lymphocytic leukemia, it normally progresses slowly. One of the most prevalent kinds of adult leukaemia is this one. A form of cancer called chronic lymphocytic leukaemia is caused by an excess of lymphocyte production in the bone marrow. Red blood cells, white blood cells, and platelets may all be impacted.
Among adult males, chronic lymphocytic leukaemia is the second most frequent malignancy. Ninety percent of cases of chronic lymphocytic leukaemia are discovered in middle age. Men and women over 50 or in middle age have a high incidence of CLL. Children are very infrequently affected by it, and persons under the age of 40 are rarely affected.
The bulk of blood stem cells that develop into healthy white blood cells in CLL are aberrant lymphocytes. The leukaemia cells are another name for the aberrant lymphocytes. These aberrant cells are not particularly effective at fighting infection. Moreover, there is less room for healthy white blood cells, red blood cells, and platelets as the amount of lymphocytes in the blood and bone marrow increases.
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This may cause infection, anemia, and easy bleeding which may result in death. In 2016, American Cancer Society has estimated that in the United States about18,960 new cases of chronic lymphocytic leukemia (CLL)and approximately 4,660 deaths by CLL are observed up till now.
Chronic Lymphocytic Leukemia Market: Drivers and Restraints
The ageing population is a driving force for the expansion of the CLL market. It is anticipated that rising cancer prevalence in both developed and developing nations, including Brazil and India, will spur market expansion. Furthermore, several medications were given unique regulatory designations. Only a small number of marketed medications are available to treat CLL because it only affects a small percentage of people.
A relatively tiny market for these medications is produced by a small or medium number of patients. So, it may or may not be viable for corporations to produce these treatments given that it would be challenging to recoup the costs associated with drug research and development. that’s why collaboration agreements and co-development are some of the key strategies adopted by top market players.
For example, recently GlaxoSmithKline plc and Genmab A/S, have entered into co-development and collaboration agreement for drug Arzerra (ofatumumab), used in the treatment of relapsed CLL. Other two important drivers for CLL treatment market are family history of blood disorders and excessive exposure to harmful chemicals. Another trend that is expected to inspire market growth is a rise in the development of combination of drug therapies.
Combination therapies for the treatment of CLL were available only in the form of chemotherapy combination drugs. Previously approved combinations were only few.However, stringent regulatory guidelines are expected to hamper market growth. Moreover, the high overall treatment cost for the therapy is another factor inhibiting the market growth. For example, GA101/RG7159 was launched in the market in 2014 by Genentech Inc (U.S.). The drug costs approximately at $409,580 for patients who take them annually.
Chronic Lymphocytic Leukemia Market overview:
Traditionally, the parenteral category has dominated the CLL treatments market. The medication is delivered via intravenous, subcutaneous, intrathecal, or intramuscular methods during parenteral ROA. Oral medicines, however, are predicted to gradually take a sizable market share. Medicines used orally are readily absorbed and start working right away. Moreover, oral ROA is crucial in situations requiring higher patient compliance, such as emergency.
For instance, CLL patients may receive one or more of the following oral tablets: imbruvica, rituximab, and idelalisib. Ibrutinib (Imbruvica) and idelalisib (Zydelig) are effective treatments for chronic lymphocytic leukaemia (CLL), which means some patients may not need chemoimmunotherapy at all.
Chronic Lymphocytic Leukemia Market: Regional Overview
Region wise, the global chronic lymphocytic leukemiamarket is classified into regions namely, North America, Latin America, Western Europe, Eastern Europe, Asia-Pacific, Japan, Middle East and Africa. North America dominated the global market for chronic lymphocytic leukemiadue to good reimbursement policies for diagnostic, therapeutic procedures and number of government organizations investigating the efficiency.
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After North America this market is followed by Europe due to increase in the number of patients suffering from CLL. Asia Pacific region is expected to perceive a significantly faster growth over the forecast period due to a number of branded drugs will become available over the next four years, with the expanding patient pool receiving greater access to such new treatments.
Chronic Lymphocytic Leukemia Market: Key Players
Some of the key players in the market of near patient molecular solution are F. Hoffman-La Roche, AbbVie, Teva Pharmaceuticals, Gilead Sciences, Novartis, and Johnson & Johnson.
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The report is a compilation of first-hand information, qualitative and quantitative assessment by industry analysts, inputs from industry experts and industry participants across the value chain.
The report provides in-depth analysis of parent market trends, macro-economic indicators and governing factors along with market attractiveness as per segments. The report also maps the qualitative impact of various market factors on market segments and geographies.
Based on Drug Route Administration (ROA) the global chronic Lymphocytic Leukemiamarket is segmented into the following:
Based on types of chemo drugs used the global chronic lymphocytic leukemiamarket is segmented into the following:
Based on end user global chronic lymphocytic leukemiamarket is segmented into the following:
Future Market Insights (ESOMAR certified market research organization and a member of Greater New York Chamber of Commerce) provides in-depth insights into governing factors elevating the demand in the market.
Mar 16, 2023
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